Cabergoline (Dostinex – Caberlin) 0.50 mg tablet is an ergot derivative, a long-acting dopamine agonist and prolactin inhibitor that is used to treat hyperprolactinemia, a condition with high prolactin levels in the blood. This medicine helps reduce the levels of prolactin in the body. Prolactin is a hormone that stimulates breast development and it aids in the formation of milk during pregnancy.
Cabergoline may also be used on its own or together with other medicines in the management of Parkinson’s disease, a disorder that affects movement of a person, causing symptoms such as tremors, muscle stiffness, slowed movement and impaired balance or walking.
Drug = Cabergoline
Strength = 0.50 mg
Manufacturer = Sun Pharma
Quantity per sleeve = 8 Tabs (for the price quoted)
How To Take Cabergoline (Dostinex – Caberlin) 0.50 mg Tablet
This medicine should be taken with food or immediately after a meal. Try to take it at the same time each day.
Cabergoline must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it suddenly as this may worsen your condition.
Take Cabergoline exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
Dosage of Cabergoline (Dostinex – Caberlin) 0.50 mg Tablet
Inhibition of physiological lactation: 1 mg as a single dose on 1st day postpartum.
Lactation suppression: 250 mcg 12 hourly for 2 days. Hyperprolactinemia-associated disorders: Initial: 0.5 mg/week, gradually increase by 0.5 mg/week at monthly interval until optimal response.
Monotherapy or adjunct therapy in Parkinson’s disease: Initial: 1 mg/day, gradually increase by 0.5-1 mg at 1 or 2 weeks interval. Recommended dose: 2-3 mg/day.
Missed Cabergoline (Dostinex – Caberlin) 0.50 mg Tablet
If you often forget to take your medicine, let your doctor and pharmacist know.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your usual dosing schedule.
Do not double a dose under any circumstances.
Signs of overdose may include the following:
- Gastric complaints
- Postural hypotension
Seek medical help immediately.
People with the following medical conditions should not take Cabergoline:
- Uncontrolled hypertension
- History of pulmonary, pericardial, and retroperitoneal fibrotic disorders
- Cardiac valvular disorders
- Toxaemia of pregnancy
- History of puerperal psychosis
- Concomitant use with dopamine antagonists
Side Effects of Cabergoline (Dostinex – Caberlin) 0.50 mg Tablet
Cabergoline may have the following side effects:
- Abdominal pain
- Breast pain
- Epigastric pain
- Postural hypotension
- Allergic skin reactions
- Cardiac valvulopathy
- Constrictive pericarditis
- Increased libido
- Leg cramps
- Pericardial effusion
- Pathological gambling
- Peripheral edema
- Pleural effusion/fibrosis
- Pulmonary/retroperitoneal fibrosis
- Digital vasospasm
- Hot flushes
- Muscle weakness
- Transient hemianopia
Warnings of Cabergoline (Dostinex – Caberlin) 0.50 mg Tablet
Do not take Cabergoline if you ever had an allergic reaction to similar medicines such as dihydroergotamine or ergotamine.
Do not use Cabergoline in people with the following conditions:
- Uncontrolled high blood pressure
- Heart valve disorder
- Scarring or thickening of the heart or lungs
Inform your doctor and pharmacist if you are taking any of these medicines:
- Ergot derivatives
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
This list does not include all medicines that may interact with Cabergoline.
How Does It Work?
Cabergoline is a long-acting dopamine D2-agonist which works by inhibiting the secretion of prolactin through hypothalamic inhibitory control exerted through the release of dopamine.
Cabergoline is used to treat the following conditions:
- Inhibition of physiological lactation
- Lactation suppression
- Hyperprolactinemia-associated disorders
- Monotherapy or adjunct therapy in Parkinson’s disease
Special Precautions and Connected Warnings
Take special precautions if you have the following conditions:
- Patients with severe cardiovascular disease
- Raynaud’s syndrome
- Peptic ulcer
- Gastrointestinal bleeding
- Renal or hepatic impairment
- Avoid alcohol
- Store between 20-25°C.
- Store in a cool, dry place away from the reach of children.
- Do not use Cabergoline that is expired or out of expiry date.